This box has everything I need for my new skincare routine. My skin is mature and dry, so it needs all the nourishing ingredients I can get. I use CleanPlus at night, followed by the Face&Neck Mask as my overnight cream. In the morning, I just use the Serum Plus+ and Night Plus+ to hydrate and energize my skin. I skip the CleanPlus in the morning, as my skin is still clean from its overnight rest. This new routine gives me all the power of Methylene Blue, Vit C , Peptides, Growth Factors and humectants like hyaluronic acid. It has taken my skin health to a noticeable new level - my fines lines are markedly improved, my skin has a beautiful smooth texture, my face is plump and glowing, and my neck is smooth. I recommend this routine to anyone over 50!